Sugar acids and derivatives
Medchemexpress LLC DCP-LA | 28399-31-7 | 98.0% | 308.50 | 25 MG
DCP-LA is a linoleic acid derivative that selectively and directly activates PKCε. It also activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. Additionally, DCP-LA inhibits the activation of caspase-3/-9 and helps protect neurons from oxidative stress-induced apoptosis.
- Selectively and directly activates PKCε
- Activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)
- Inhibits protein phosphatase-1 (PP-1)
- Stimulates AMPA receptor exocytosis
- Inhibits activation of caspase-3/-9
- Helps protect neurons from oxidative stress-induced apoptosis
- Facilitates hippocampal synaptic transmission
- Exhibits protective effect against ischemic brain damage
BIOHIPPO T-bet-TAL-BSD LV
T-bet-TAL-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC Magenta-β-D-GlcA (5-bromo-6-chloro-3-indolyl β-D-glucuronide cyclohexylammonium) | 144110-43-0 | 99.8% | 521.79 | 25 MG
Magenta-β-D-GlcA is a biochemical reagent suitable for life science research. This organic compound is intended for research use only and not for patient use. It typically appears as a white to off-white solid.
- Can be used as a biological material or organic compound
- Intended for life science related research
- Appears as a white to off-white solid
- Research use only
- Not sold to patients
- Solubility in DMSO: 50 mg/mL (needs sonication; use newly opened DMSO)
- Stock solution storage: -80°C for 6 months, or -20°C for 1 month (sealed, away from moisture)
- Product storage: -20°C, sealed, away from moisture
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 50 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, helps heal ulcerative colitis, and improves the intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin. It also modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones.
- Shows anti-inflammatory activity
- Helps heal ulcerative colitis
- Improves intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin
- Modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Sigma Aldrich Fine Chemicals Biosciences Alginic acid from brown algae | 9005-32-7 | MFCD00081309 | 100G
Alginic acid from brown algae | 9005-32-7 | MFCD00081309 | 100G
Sigma Aldrich Fine Chemicals Biosciences Heparin SepharoseR 6 Fast
Heparin Sepharose(R) 6 Fast Flow is a well established BioProcess affinity medium designed for capture or intermediate purification steps. This medium is extensively used for industrial purification of several marketed plasma proteins.Heparin Sepharose(R) 6 Fast Flow is a member of the Cytiva range of affinity chromatography media for capture and intermediate purification.Heparin Sepharose(R) 6 Fast Flow is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the media is solely dictated by the heparin ligand.This medium allows for fast and reliable separations of biomolecules with an affinity for heparin including antithrombin III coagulation factors and other plasma proteins. Additional applications include DNA binding proteins lipoproteins protein synthesis factors enzymes that act on nucleic acids and steroid receptors.Heparin Sepharo
Medchemexpress LLC 4-Methylumbelliferyl β-D-cellobioside | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 100 MG
4-Methylumbelliferyl β-D-cellobioside is a substrate for cellulase. It can be hydrolyzed to produce fluorescent 4-methylumbelliferone, which is used to study the kinetics of cellulases.
- Substrate for cellulase
- Produces fluorescent 4-methylumbelliferone
- Used to study the kinetics of cellulases
Medchemexpress LLC Tert-butyl N-(1H-indol-4-yl)carbamate | 819850-13-0 | MFCD04973303 | 95.0-98.0% | 232.28 g/mol | C13H16N2O2 | 100 MG
tert-Butyl 1H-indol-4-ylcarbamate is a synthetic intermediate used in pharmaceutical and medicinal chemistry research. Supplied as a powder for laboratory use and intended for research use only, it serves as a building block in small-molecule synthesis and related workflows.
- Used as a synthetic intermediate in pharmaceutical synthesis.
- Supplied as a powder suitable for laboratory handling.
- Available in multiple pack sizes, including 100 mg, 250 mg, 500 mg, and 1 g.
- Identified by CAS 819850-13-0 and molecular formula C13H16N2O2.
- Storage: powder stable at -20°C (up to 3 years) or 4°C (up to 2 years).
- Product datasheet available; purity and batch details provided by suppliers.
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | MFCD32689543 | 96.4% | 897.90 | C42H47N3O17S | 25 MG
MAC glucuronide linker-1 is a cleavable antibody-drug conjugate (ADC) linker intended for research use, designed to release payloads through glucuronide cleavage under target conditions.
- Cleavable glucuronide-based linker for antibody-drug conjugates.
- Intended for research use only.
- CAS number 2222981-71-5.
- Purity 96.36%.
- Molecular weight 897.90.
- Chemical formula C42H47N3O17S.
- Appearance white to off-white solid.
- Storage: store under nitrogen; in solvent, -80°C for 6 months and -20°C for 1 month.
Apexbio Technology LLC Amyloid Beta-Peptide (1-40) (human) 131438-79-4 25mg
Amyloid Beta-Peptide (1-40) (human) (CAS 131438-79-4) is a synthetic peptide composed of 40 amino acids identical to residues 1-40 of human amyloid-beta (A ) characterized by molecular weight of 4329 8 Da Derived from amyloid precursor protein (APP) via sequential proteolytic cleavage by - and -secretases A peptides form extracellular plaques and vascular deposits commonly observed in Alzheimer s disease pathology A 40 is among the predominant isoforms generated primarily through cleavage in the transmembrane region of APP within the Golgi apparatus As a model peptide A (1-40) is widely employed to study amyloid fibril formation neurotoxicity mechanisms and therapeutic strategies targeting Alzheimer s disease progression
Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[(4-O-β-D-glucopyranosyl-ẞ-D-glucopyranosyl)oxy]-4-methyl- | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 25 MG
4-Methylumbelliferyl β-D-cellobioside is a fluorescent dye and a substrate for cellulase. With a purity of 99.4%, this compound has a molecular weight of 500.45.
- Functions as a fluorescent dye
- Acts as a substrate for cellulase
- Purity: 99.4%
- Molecular weight: 500.45
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month